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Micronutrient, Antioxidants Panel
Test Code10187
CPT Codes
82180, 82542, 84446, 84590
Includes
10178 - Micronutrient, Coenzyme Q10 (CoQ10)
10179 - Micronutrient, Vitamin A (Retinol)
10181 - Micronutrient, Vitamin C
10183 - Micronutrient, Vitamin E (Alpha Tocopherol and Beta Gamma Tocopherol)
10179 - Micronutrient, Vitamin A (Retinol)
10181 - Micronutrient, Vitamin C
10183 - Micronutrient, Vitamin E (Alpha Tocopherol and Beta Gamma Tocopherol)
Preferred Specimen
3 mL serum - protected from light (See Collection Instructions)
Patient Preparation
Overnight fasting required.
Avoid taking Coenzyme Q10 supplements the morning of the test.
Refrain from eating fruits or taking vitamin C supplements 24 hours prior to collection.
Minimum Volume
1.5 mL
Instructions
Patients should be 18 years of age or greater.
Gently invert specimen 5 times (DO NOT SHAKE!), allow to clot for 30 -60 min at room temperature, centrifuge 10 minutes.
Separate serum into 3 amber plastic transport tubes:
1 mL (0.5 mL min) for Vitamin A and E, protect from light, ship frozen (can be refrigerated).
1 mL (0.5 mL min) for Vitamin C, freeze immediately, protect from light, ship frozen.
1 mL (0.5 mL min) for CoQ10, protect from light, ship refrigerated. Do not ship on dry ice.
Vitamin C must be shipped on dry ice.
Coenzyme Q10 must NOT be shipped on dry ice.
Gently invert specimen 5 times (DO NOT SHAKE!), allow to clot for 30 -60 min at room temperature, centrifuge 10 minutes.
Separate serum into 3 amber plastic transport tubes:
1 mL (0.5 mL min) for Vitamin A and E, protect from light, ship frozen (can be refrigerated).
1 mL (0.5 mL min) for Vitamin C, freeze immediately, protect from light, ship frozen.
1 mL (0.5 mL min) for CoQ10, protect from light, ship refrigerated. Do not ship on dry ice.
Vitamin C must be shipped on dry ice.
Coenzyme Q10 must NOT be shipped on dry ice.
Transport Container
Ship in amber tube or wrap specimen tubes in aluminum foil to protect from light
Transport Temperature
Vitamins A and E, Coenzyme Q10: Refrigerated (cold packs)
Vitamin C: Frozen -70° C
Vitamin C: Frozen -70° C
Specimen Stability
Coenzyme Q10 (CoQ10)
Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 6 weeks
Vitamin A and Vitamin E
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Vitamin C
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen -20° C: 8 hours
Frozen -70° C: 35 days
Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 6 weeks
Vitamin A and Vitamin E
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Vitamin C
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen -20° C: 8 hours
Frozen -70° C: 35 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Received room temperature • Not protected from light • Vitamin C received refrigerated
Methodology
Chromatography • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Set up and Report available: See individual assays
Reference Range
| Coenzyme Q10 (CoQ10) | >35 ug/mL |
Vitamin A (Retinol)
| 18-19 years | 26-72 mcg/dL |
| >19 years | 38-98 mcg/dL |
Vitamin C
| Male ≥18 years | 0.2-2.1 mg/dL |
| Female ≥18 years | 0.3-2.7 mg/dL |
Vitamin E
| Vitamin E, Alpha Tocopherol | ≥18 years | 5.7-19.9 mg/L |
| Vitamin E, Beta-Gamma Tocopherol | ≥18 years | <4.4 mg/L |
