Micronutrient, Vitamin E

Test Code

10183

CPT Codes
84446

Includes

Vitamin E, Alpha Tocopherol
Vitamin E, Beta-Gamma Tocopherol

Preferred Specimen

2 mL serum - protected from light

Patient Preparation
Overnight fasting is required

Minimum Volume

0.7 mL

Instructions

Patients should be 18 years of age or greater.

Separate from cells within 24 hours after clotting. Send serum in an amber tube. If an amber tube is not available, wrap the tube in aluminum foil to protect from light.

Transport Container

Amber transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Received room temperature • Not protected from light • Plasma

Methodology
Chromatography

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 2-3 days

Reference Range

Vitamin E, Alpha Tocopherol

≥18 years

5.7-19.9 mg/L

Reference range not available for individuals <18 years for this micronutrient test.

Vitamin E, Beta-Gamma Tocopherol

≥18 years

<4.4 mg/L

Reference range not available for individuals <18 years for this micronutrient test.

Clinical Significance

Deficiency of Vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of Vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of Vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.