Tacrolimus High Sens LC/MS/MS

Test Code
TACRO


Quest Code
13228


CPT Codes
80197

Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube


Patient Preparation
Collect specimen 1 hour prior to next dose (12 hour trough)

Minimum Volume
1 mL


Transport Container
EDTA (lavender-top) tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 60 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen


Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Setup Schedule
Daily


Report Available
1 day


Reference Range
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post- transplant, co-administration of other drugs, and drug formulation.
The following trough range is a suggested guideline: 5.0-20.0 mcg/L.


Clinical Significance
Tacrolimus is an immunosuppressant drug which has been shown to be effective for the treatment of rejection following transplantation.


Performing Laboratory
Quest Diagnostics LLC
200 Forest Street, 3rd Floor, Suite B
Marlborough, MA 01752-3023




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.