Creatine Kinase

Test Code
CK


CPT Codes
82550

Preferred Specimen
GREEN Lithium Heparin Plasma


Minimum Volume
0.25 mL


Other Acceptable Specimens
SST Serum Separator, Red No Gel


Instructions
Separate from cells within 4 hours of collection


Transport Container
GREEN Lithium Heparin


Transport Temperature
Room Temperature


Specimen Stability
Room Temp: 4 hours; Refrigerated: 5 Days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not separated from cells within 4 hours of collection, Gross hemoloysis


Methodology
Vitros 7600/3400

Reference Range
Female: 30-135 U/L; Male: 55-170 U/L; Critical Value: >6000 U/L


Clinical Significance
found mainly in skeletal and cardiac muscle. CK’s physiological role is associated with ATP generation for contractile or transport systems. Serum CK is almost always increased following acute myocardial infarction or skeletal muscle damage. The enzyme is commonly elevated in myocarditis of any cause, cerebrovascular accidents, rhabdomyolysis, polymyositis, and acute physical exertion. CK is also increased in the muscular dystrophies; in Duchenne’s muscular dystrophy, CK elevations of 20–200 times normal are common. Low CK may reflect decreased muscle mass or muscle wasting. Reference for CK must consider the age, gender, and physical activity of the person. Low serum CK activities are common in the elderly, in the bedridden, and in patients with advanced malignancy


Performed By
RFGH Laboratory

Performing Laboratory
RFGH Laboratory



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.