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Creatine Kinase
Test CodeCK
CPT Codes
82550
Preferred Specimen
GREEN Lithium Heparin Plasma
Minimum Volume
0.25 mL
Other Acceptable Specimens
SST Serum Separator, Red No Gel
Instructions
Separate from cells within 4 hours of collection
Transport Container
GREEN Lithium Heparin
Transport Temperature
Room Temperature
Specimen Stability
Room Temp: 4 hours; Refrigerated: 5 Days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not separated from cells within 4 hours of collection, Gross hemoloysis
Methodology
Vitros 7600/3400
Reference Range
Female: 30-135 U/L; Male: 55-170 U/L; Critical Value: >6000 U/L
Clinical Significance
found mainly in skeletal and cardiac muscle. CK’s physiological role is associated with ATP generation for contractile or transport systems. Serum CK is almost always increased following acute myocardial infarction or skeletal muscle damage. The enzyme is commonly elevated in myocarditis of any cause, cerebrovascular accidents, rhabdomyolysis, polymyositis, and acute physical exertion. CK is also increased in the muscular dystrophies; in Duchenne’s muscular dystrophy, CK elevations of 20–200 times normal are common. Low CK may reflect decreased muscle mass or muscle wasting. Reference for CK must consider the age, gender, and physical activity of the person. Low serum CK activities are common in the elderly, in the bedridden, and in patients with advanced malignancy
Performed By
RFGH Laboratory
Performing Laboratory
RFGH Laboratory

