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Creatinine Clearance Urine
Test CodeCRCL
CPT Codes
82575
Includes
Serum Creatinine, Urine Creatinine 24 hr, Creatinine Clearance
Preferred Specimen
SST Serum Separator & 24 Hour Urine Jug
Transport Container
24 Hour Urine Jug
Transport Temperature
Store refrigerated during collection; Transport at Room Temp
Specimen Stability
Room Temp: 3 Days; Refrigerated: 5 Days
Reference Range
50 - 90 mL/min
Clinical Significance
Serum creatinine and urinary creatinine excretion is a function of lean body mass in normal persons and shows little or no response to dietary changes. The serum creatinine concentration is higher in men than in women. Since urinary creatinine is excreted mainly by glomerular filtration, with only small amounts due to tubular secretion, serum creatinine and a 24-hour urine creatinine excretion can be used to estimate the glomerular filtration rate. Serum creatinine is increased in acute or chronic renal failure, urinary tract obstruction, reduced renal blood flow, shock, dehydration, and rhabdomyolysis. Causes of low serum creatinine concentration include debilitation and decreased muscle mass. Exercise may cause an increased creatinine clearance. The creatinine clearance rate is unreliable if the urine flow is low.
Performed By
RFGH Laboratory
