Valproate

Message

For patients receiving valproic acid orally the blood sample should be drawn immediately before the next dose because of its short half-life. Valproic acid samples should be monitored at a consistent time of day because concentration is affected by circadian
rhythm.

Test Code

VALP

CPT Codes
80164

Preferred Specimen

GREEN Lithium Heparin Plasma

Minimum Volume

0.50 mL

Other Acceptable Specimens

SST Serum Separator, Red No Gel

Instructions

Separate from cells within 4 hour of collection

Transport Container

GREEN Lithium Heparin

Transport Temperature

Room Temperature

Specimen Stability

Room Temperature: 1 day; Refrigerated: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Not separated from cells within 4 hours of collection

Methodology
Vitros 7600

Reference Range

Therapeutic Range: 50-120 ug/mL; Critical Value: >150 ug/Ml

Clinical Significance

Serum or plasma valproic acid measurements are used in the diagnosis and treatment of valproic acid overdose and in monitoring levels of valproic acid to ensure appropriate therapy.

Performed By
RFGH Laboratory

Performing Laboratory
RFGH Laboratory

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.