Phenytoin (Dilantin)

Message
Phenytoin specimens should be drawn just before the next dose for trough . If toxicity is suspected, specimens may be drawn at any time.


Test Code
PTN


CPT Codes
80185

Preferred Specimen
GREEN Lithium Heparin Plasma


Minimum Volume
0.25 mL


Other Acceptable Specimens
SST Serum Separator, Red No Gel


Instructions
Separate from cells within 4 hour of collection


Transport Container
GREEN Lithium Heparin


Transport Temperature
Room Temperature


Specimen Stability
Room Temperature: 8 hours; Refrigerated: 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not separated from cells within 4 hours of collection, Gross hemolysis


Methodology
Vitros 7600/3400

Reference Range
Therapeutic Range: 10-20 ug/mL; Critical Value: >30 ug/mL


Clinical Significance
Phenytoin is a widely prescribed anticonvulsant drug used in the treatment of generalized and partial seizures. Phenytoin measurements are used to monitor patient compliance and therapy and to diagnose potential overdose.


Performed By
RFGH Laboratory

Performing Laboratory
RFGH Laboratory



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.