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Phenytoin (Dilantin)
MessagePhenytoin specimens should be drawn just before the next dose for trough . If toxicity is suspected, specimens may be drawn at any time.
Test Code
PTN
CPT Codes
80185
Preferred Specimen
GREEN Lithium Heparin Plasma
Minimum Volume
0.25 mL
Other Acceptable Specimens
SST Serum Separator, Red No Gel
Instructions
Separate from cells within 4 hour of collection
Transport Container
GREEN Lithium Heparin
Transport Temperature
Room Temperature
Specimen Stability
Room Temperature: 8 hours; Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not separated from cells within 4 hours of collection, Gross hemolysis
Methodology
Vitros 7600/3400
Reference Range
Therapeutic Range: 10-20 ug/mL; Critical Value: >30 ug/mL
Clinical Significance
Phenytoin is a widely prescribed anticonvulsant drug used in the treatment of generalized and partial seizures. Phenytoin measurements are used to monitor patient compliance and therapy and to diagnose potential overdose.
Performed By
RFGH Laboratory
Performing Laboratory
RFGH Laboratory

