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Acetaminophen
MessageAcetaminophen specimens should not be drawn earlier than four hours after ingestion. If the time of ingestion is not known, two or more blood samples taken at two three-hour intervals may be used to estimate acetaminophen half-life and assess toxicity
Test Code
ACET
CPT Codes
80329
Preferred Specimen
GREEN Lithium Heparin Plasma
Minimum Volume
0.25 mL
Other Acceptable Specimens
SST Serum Separator, Red No Gel
Instructions
Separate from cells within 5 days of collection
Transport Container
GREEN Lithium Heparin
Transport Temperature
Room Temperature
Specimen Stability
Room Temperature: 7 days; Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not separated from cells within 5 days of collection, Gross hemolysis
Methodology
Vitros 7600/3400
Reference Range
0-10 ug/mL; Critical Value: >150 ug/mL
Clinical Significance
Acetaminophen is a commonly used therapeutic drug with analgesic and antipyretic properties. Acetaminophen measurements are useful in the diagnosis and treatment of acute overdose, which can result in severe hepatotoxicity and nephrotoxicity. Acetaminophen specimens should not be drawn earlier than four hours after ingestion. If the time of ingestion is not known, two or more blood samples taken at two three-hour intervals may be used to estimate acetaminophen half-life
and assess toxicity
and assess toxicity
Performed By
RFGH Laboratory
Performing Laboratory
RFGH Laboratory
