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Total Protein
Test CodeTP
CPT Codes
84155
Preferred Specimen
GREEN Lithium Heparin Plasma
Minimum Volume
0.25 mL
Other Acceptable Specimens
SST Serum Separator, Red No Gel
Instructions
Separate from cells within 4 hours of collection
Transport Container
GREEN Lithium Heparin
Transport Temperature
Room Temperature
Specimen Stability
Room Temp: 4 Hours; Refrigerated: 3 Days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not separated from cells within 4 hours of collection, gross hemolysis
Methodology
Vitros 7600/3400
Reference Range
6.3-8.2 g/dL
Clinical Significance
Serum proteins transport drugs and metabolites and maintain plasma osmotic pressure. Most serum proteins are synthesized in the liver, with the exception of gamma globulins. One of the most important serum proteins produced in the liver is albumin. Total serum protein concentration can be used for evaluation of nutritional status. Causes of high total serum protein concentration include dehydration, Waldenström’s macroglobulinemia, multiple myeloma, hyperglobulinemia, granulomatous diseases, and some tropical diseases. Total protein concentration is occasionally increased in collagen diseases, lupus erythematosus, and other instances of chronic infection or inflammation. Causes of low total serum protein concentration include pregnancy, excessive intravenous fluid administration, cirrhosis or other liver diseases, chronic alcoholism, heart failure, nephrotic syndrome, glomerulonephritis, neoplasia, protein-losing enteropathies, malabsorption, and severe malnutrition.
Performed By
RFGH Laboratory
Performing Laboratory
RFGH Laboratory
