Folate

Test Code
FOL


CPT Codes
82746

Preferred Specimen
GREEN Lithium Heparin Plasma


Minimum Volume
0.50 mL


Other Acceptable Specimens
SST Serum Separator, Red No Gel


Instructions
Separate from cells within 2 hours of collection


Transport Container
GREEN Lithium Heparin


Transport Temperature
Room Temperature


Specimen Stability
Refrigerated: 7 Days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis


Methodology
Vitros 7600

Reference Range
2.76->20.0 ng/mL


Clinical Significance
Folate and vitamin B12 are necessary for DNA synthesis, and consequently normal red blood cell maturation. Folate deficiency can lead to macrocytic (megaloblastic) anemia. Low folate intake, malabsorption as a result of gastrointestinal diseases, pregnancy and
the use of drugs such as phenytoin, oral contraceptives and excessive concentrations of alcohol are causes of folate
deficiency. Low serum folate concentrations are an early indication of folate depletion and precede depletion in the
tissues. 2 Adequate folate concentrations during pregnancy are also important in the prevention of neural tube defects
(NTD) in infants. Folate supplementation prior to conception and in the first weeks of pregnancy reduces the incidence of
NTD affected births


Performed By
RFGH Laboratory

Performing Laboratory
RFGH Laboratory



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.