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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Folate
Test CodeFOL
CPT Codes
82746
Preferred Specimen
GREEN Lithium Heparin Plasma
Minimum Volume
0.50 mL
Other Acceptable Specimens
SST Serum Separator, Red No Gel
Instructions
Separate from cells within 2 hours of collection
Transport Container
GREEN Lithium Heparin
Transport Temperature
Room Temperature
Specimen Stability
Refrigerated: 7 Days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis
Methodology
Vitros 7600
Reference Range
2.76->20.0 ng/mL
Clinical Significance
Folate and vitamin B12 are necessary for DNA synthesis, and consequently normal red blood cell maturation. Folate deficiency can lead to macrocytic (megaloblastic) anemia. Low folate intake, malabsorption as a result of gastrointestinal diseases, pregnancy and
the use of drugs such as phenytoin, oral contraceptives and excessive concentrations of alcohol are causes of folate
deficiency. Low serum folate concentrations are an early indication of folate depletion and precede depletion in the
tissues. 2 Adequate folate concentrations during pregnancy are also important in the prevention of neural tube defects
(NTD) in infants. Folate supplementation prior to conception and in the first weeks of pregnancy reduces the incidence of
NTD affected births
the use of drugs such as phenytoin, oral contraceptives and excessive concentrations of alcohol are causes of folate
deficiency. Low serum folate concentrations are an early indication of folate depletion and precede depletion in the
tissues. 2 Adequate folate concentrations during pregnancy are also important in the prevention of neural tube defects
(NTD) in infants. Folate supplementation prior to conception and in the first weeks of pregnancy reduces the incidence of
NTD affected births
Performed By
RFGH Laboratory
Performing Laboratory
RFGH Laboratory

