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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Beta-Hydroxybutyrate
Test CodeBHBT
Alias/See Also
BHB
CPT Codes
82010
Preferred Specimen
GREEN Lithium Heparin Plasma
Minimum Volume
0.5 mL
Other Acceptable Specimens
SST Serum Separator, Red No Gel
Instructions
Separate from cells within 2 hour of collection
Transport Container
GREEN Lithium Heparin
Transport Temperature
Room Temperature
Specimen Stability
Refrigerated: 7 Days
Methodology
Vitros 7600
Reference Range
0.02-0.27 mmol/L
Clinical Significance
Ketosis is a common feature in acutely ill patients. In subjects suffering from starvation, acute alcohol abuse, or diabetes mellitus, ketosis can result in severe life threatening metabolic acidosis.1 The presence and degree of ketosis can be determined by measuring blood levels of ß-hydroxybutyrate.
Ordinarily, ß-hydroxybutyrate is the ketoacid present in the greatest amount in serum. It accounts for approximately 75% of the ketone bodies which also contain acetoacetate and acetone.2, 3, 4 During periods of ketosis, ß-hydroxybutyrate increases even more than the other two ketoacids, acetoacetate and acetone, and has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.5, 6, 7, 8
In diabetics, the measurement of ß-hydroxybutyrate as well as the blood glucose is needed for the assessment of the severity of diabetic coma and is essential for the exclusion of hyperosmolar non-ketotic diabetic coma. Moreover, the insulin requirements are often based on the extent of the existing hyperketonemia9 shown by the blood levels of ß-hydroxybutyrate is therefore extremely important in the assessment of ketosis.
Ketosis is a common feature in acutely ill patients. In subjects suffering from starvation, acute alcohol abuse, or diabetes mellitus, ketosis can result in severe life threatening metabolic acidosis.1 The presence and degree of ketosis can be determined by measuring blood levels of ß-hydroxybutyrate.
Ordinarily, ß-hydroxybutyrate is the ketoacid present in the greatest amount in serum. It accounts for approximately 75% of the ketone bodies which also contain acetoacetate and acetone.2, 3, 4 During periods of ketosis, ß-hydroxybutyrate increases even more than the other two ketoacids, acetoacetate and acetone, and has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.5, 6, 7, 8
In diabetics, the measurement of ß-hydroxybutyrate as well as the blood glucose is needed for the assessment of the severity of diabetic coma and is essential for the exclusion of hyperosmolar non-ketotic diabetic coma. Moreover, the insulin requirements are often based on the extent of the existing hyperketonemia9 shown by the blood levels of ß-hydroxybutyrate is therefore extremely important in the assessment of ketosis.
Ordinarily, ß-hydroxybutyrate is the ketoacid present in the greatest amount in serum. It accounts for approximately 75% of the ketone bodies which also contain acetoacetate and acetone.2, 3, 4 During periods of ketosis, ß-hydroxybutyrate increases even more than the other two ketoacids, acetoacetate and acetone, and has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.5, 6, 7, 8
In diabetics, the measurement of ß-hydroxybutyrate as well as the blood glucose is needed for the assessment of the severity of diabetic coma and is essential for the exclusion of hyperosmolar non-ketotic diabetic coma. Moreover, the insulin requirements are often based on the extent of the existing hyperketonemia9 shown by the blood levels of ß-hydroxybutyrate is therefore extremely important in the assessment of ketosis.
Ketosis is a common feature in acutely ill patients. In subjects suffering from starvation, acute alcohol abuse, or diabetes mellitus, ketosis can result in severe life threatening metabolic acidosis.1 The presence and degree of ketosis can be determined by measuring blood levels of ß-hydroxybutyrate.
Ordinarily, ß-hydroxybutyrate is the ketoacid present in the greatest amount in serum. It accounts for approximately 75% of the ketone bodies which also contain acetoacetate and acetone.2, 3, 4 During periods of ketosis, ß-hydroxybutyrate increases even more than the other two ketoacids, acetoacetate and acetone, and has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.5, 6, 7, 8
In diabetics, the measurement of ß-hydroxybutyrate as well as the blood glucose is needed for the assessment of the severity of diabetic coma and is essential for the exclusion of hyperosmolar non-ketotic diabetic coma. Moreover, the insulin requirements are often based on the extent of the existing hyperketonemia9 shown by the blood levels of ß-hydroxybutyrate is therefore extremely important in the assessment of ketosis.
Performed By
RFGH Laboratory
Performing Laboratory
RFGH Laboratory
