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Complement, Total (CH50)
Test Code618
Alias/See Also
LAB154
CPT Codes
86162
Preferred Specimen
1 mL frozen serum
Minimum Volume
0.5 mL
Instructions
Draw sample without anticoagulant. Allow to clot. Separate serum into a plastic tube and freeze sample within one hour of time drawn.
With mutiple tests, submit a separate tube for each test. Do not submit the sample in a glass tube.
With mutiple tests, submit a separate tube for each test. Do not submit the sample in a glass tube.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days
Refrigerated: Unacceptable
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Received thawed • Received room temperature • Received refrigerated
Methodology
Liposome
Setup Schedule
Sun, mon, wed-fri
Report Available
3-5 days
Reference Range
31-60 U/mL
Clinical Significance
CH50 is a screening test for total complement activity. Levels of complement may be depressed in genetic deficiency, liver disease, chronic glomerulonephritis, rheumatoid arthritis, hemolytic anemias, graft rejection, systemic lupus erythematosis, acute glomerulonephritis, subacute bacterial endocarditis and cryoglobulinemia. Elevated complement may be found in acute inflammatory conditions, leukemia, Hodgkin's Disease, sarcoma, and Behcet's Disease.