Cryptococcal Antigen, Latex Screen with Reflex to Titer

Test Code
11196


Alias/See Also
LAB779
 


CPT Codes
86403

Includes
If Cryptococcal Antigen Screen is Detected, then Cryptococcal Antigen, Latex Titer will be performed at an additional charge (CPT code(s): 86406).


Preferred Specimen
1 mL CSF or 2 mL serum


Minimum Volume
0.5 mL CSF or serum


Instructions
Centrifuge serum specimens within 1 hour of collection. Transfer serum to clean transport tube. Refrigerate samples and transport on refrigerant coolant or freeze samples and transport on dry ice to the laboratory.


Transport Container
CSF: Sterile screw-cap tube
Serum: Transport tube


Transport Temperature
Serum from red-top tube (no gel): Refrigerated or frozen
Serum separator tube (SST): Refrigerated (cold-packs)
CSF: Refrigerated (cold-packs) or frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days


Methodology
Latex Agglutination (LA)

Setup Schedule
Tues-sat


Report Available
1-3 days


Limitations
Patients with capnocytophaga canimorsus and tichosporon beigelli infections may test falsely-positive.


Reference Range
Not detected


Clinical Significance
The encapsulated soil yeast Cryptococcus neoformans causes Cryptococcosis. Pulmonary infection is acquired by inhalation of the organism and is usually subclinical in the immunocompetent host. Dissemination may occur in an immunocompromised patient, often to the meninges.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.