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Cryptococcal Antigen, Latex Screen with Reflex to Titer
Test Code11196
Alias/See Also
LAB779
CPT Codes
86403
Includes
If Cryptococcal Antigen Screen is Detected, then Cryptococcal Antigen, Latex Titer will be performed at an additional charge (CPT code(s): 86406).
Preferred Specimen
1 mL CSF or 2 mL serum
Minimum Volume
0.5 mL CSF or serum
Instructions
Centrifuge serum specimens within 1 hour of collection. Transfer serum to clean transport tube. Refrigerate samples and transport on refrigerant coolant or freeze samples and transport on dry ice to the laboratory.
Transport Container
CSF: Sterile screw-cap tube
Serum: Transport tube
Serum: Transport tube
Transport Temperature
Serum from red-top tube (no gel): Refrigerated or frozen
Serum separator tube (SST): Refrigerated (cold-packs)
CSF: Refrigerated (cold-packs) or frozen
Serum separator tube (SST): Refrigerated (cold-packs)
CSF: Refrigerated (cold-packs) or frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days
Refrigerated: 7 days
Frozen: 60 days
Methodology
Latex Agglutination (LA)
Setup Schedule
Tues-sat
Report Available
1-3 days
Limitations
Patients with capnocytophaga canimorsus and tichosporon beigelli infections may test falsely-positive.
Reference Range
Not detected
Clinical Significance
The encapsulated soil yeast Cryptococcus neoformans causes Cryptococcosis. Pulmonary infection is acquired by inhalation of the organism and is usually subclinical in the immunocompetent host. Dissemination may occur in an immunocompromised patient, often to the meninges.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |