Erythropoietin

Test Code

427

Alias/See Also

LAB873
EPO

CPT Codes
82668

Preferred Specimen

1 mL serum

Patient Preparation
Due to diurnal variation, it is recommended that specimens be collected between 7:30 am and noon

Minimum Volume

0.5 mL

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 10 days
Refrigerated: 18 days
Frozen: 28 days

Methodology
Immunoassay (IA)

Setup Schedule

Mon, wed, fri, sat

Report Available

3-6 days

Reference Range

	Male (mIU/mL)	Female (mIU/mL)
<1 Year	Not established	Not established
1-3 Years	1.7-17.9	2.1-15.9
4-6 Years	3.5-21.9	2.9-8.5
7-9 Years	1.0-13.5	2.1-8.2
10-12 Years	1.0-14.0	1.1-9.1
13-15 Years	2.2-14.4	3.8-20.5
16-18 Years	1.5-15.2	2.0-14.2
>18 Years	2.6-18.5	2.6-18.5

Clinical Significance

Elevated levels of serum erythropoietin (EPO) occur in patients with anemias due to increased red cell destruction in hemolytic anemia and also in secondary polycythemias associated with impaired oxygen delivery to the tissues, impaired pulmonary oxygen exchange, abnormal hemoglobins with increased oxygen affinity, constriction of the renal vasculature, and inappropriate EPO secretion caused by certain renal and extrarenal tumors. Normal or depressed levels may occur in anemias due to increased oxygen delivery to tissues, in hypophosphatemia, and in polycythemia vera.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.