A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Blastomyces Antibody, Complement Fixation, Serum
Test Code933
CPT Codes
86612
Preferred Specimen
1 mL serum
Minimum Volume
0.1 mL
Instructions
Note: For CSF use test code 5294 - Blastomyces Antibody Compliment Fixation, CSF.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Complement Fixation (CF)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Tues-sat
Report Available
4-7 days
Reference Range
Titer | Interpretation |
<1:8 | Antibody Not Detected |
≥1.8 | Antibody Detected |
Clinical Significance
Although titers of 1:8 and greater are considered positive, confirmed serological diagnosis of blastomycosis by the CF test requires a four-fold or greater increase in titer between acute and convalescent specimens, and lack of corresponding titers to C. immitis and H. capsulatum. Specificity can only be demonstrated by immunodiffusion procedures. A negative CF test does not rule out the diagnosis of active blastomycosis, as less than 50% of sera from patients with proven blastomycosis are positive by this assay.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |