Ri Antibody Screen with Reflex to Titer and Western Blot

Test Code
10140


Alias/See Also
LAB00297
RI AB


CPT Codes
86255

Includes
If Ri Antibody Screen, IFA is positive, then Ri Antibody, WB will be performed at an additional charge (CPT code(s): 84181).
If Ri Antibody, WB is positive, then Ri Antibody, Titer will be performed at an additional charge (CPT code(s): 86256).


Preferred Specimen
0.5 mL serum


Patient Preparation
Overnight fasting is preferred

Minimum Volume
0.2 mL


Transport Container
Transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days


Methodology
Immunofluorescence Assay (IFA) • Western Blot (WB)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Mon, wed, fri


Report Available
1-6 days


Reference Range
Ri Ab Screen, IFANegative
  Ri Ab, WBNegative
  Ri Ab, Titer<1:40


Clinical Significance
Anti-Ri can be detected in patients with the paraneoplastic opsoclonus/myoclonus syndrome. Neoplasms most often associated with Anti-Ri include breast cancer, gynecological cancers, and small cell lung cancer.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.