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Prostaglandin D2 (Random Urine)
Test Code10180
Alias/See Also
LAB1075
PGD2
PGD2
CPT Codes
84150<br><strong>This test is not available for New York patient testing.</strong>
Preferred Specimen
10 mL frozen urine collected in a sterile leak-proof container
Patient Preparation
Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.
Minimum Volume
5 mL
Instructions
Ship specimen frozen on dry ice
Transport Container
Plastic urine container
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 6 months
Refrigerated: Unacceptable
Frozen: 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
24-hour urine collections
Methodology
Enzyme Immunoassay (EIA)
FDA Status
This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.
This test is not available for New York patient testing.
Setup Schedule
Mon-Fri
Report Available
15 days
Reference Range
<175 ng/g Creatinine
Clinical Significance
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.
Performing Laboratory
Interscience Institute |
944 W Hyde Park Blvd |
Inglewood, CA 90302-3308 |