Epstein-Barr Virus DNA, Quantitative, Real-Time PCR

Test Code

10186

Alias/See Also

LAB1373
EBV QNT
MONONUCLEOSIS

CPT Codes
87799

Preferred Specimen

1 mL whole blood collected in an EDTA (lavender-top) tube or
Plasma collected in an EDTA (lavender-top) tube or
Serum or
CSF collected in a sterile plastic leak-proof container

Minimum Volume

0.5 mL

Other Acceptable Specimens

Bronchoalveolar lavage collected in: Sterile plastic leak-proof container

Instructions

⁠⁠⁠⁠⁠⁠⁠CSF: Submit in a sterile plastic container and store refrigerated or frozen.

Note: Avoid repeated freezing and thawing.

Transport Container

See Preferred Specimen(s)

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Whole blood
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: Unacceptable

All other sample types
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Heparin anticoagulant

Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Daily

Report Available

2-3 days

Reference Range

EBV DNA, QN PCR	Not Detected (copies/mL)
EBV DNA, QN PCR	Not Detected (Log copies/mL)

Clinical Significance

Monitoring EBV DNA levels by quantitative PCR in patients at risk of EBV-associated lymphoproliferative disorders may allow timely recognition of virus reactivation and permit installment of antiviral treatment. Reportable Range is 200-2,000,000 copies/mL (2.30-6.30 Log Copies/mL).

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.