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Human Platelet Antigen 1 Genotype
Test Code10707
Alias/See Also
LAB00213
CPT Codes
81105
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Transport Container
EDTA (lavender-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: Unacceptable
Refrigerated: 14 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Frozen whole blood
Methodology
DNA-Based Capture Binding Assay
Setup Schedule
Tues
Report Available
3-10 days
Clinical Significance
Human Platelet Antigen (HPA) polymorphism can lead to alloimmunization that clinically can manifest as neonatal alloimmune thrombocytopenia or post-transfusion thrombocytopenia purpura. HPA-1 genotyping allows screening for potential neonatal immunization in pregnancy.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |