Cortisol, Free, 24-Hour Urine with Creatinine, LC/MS/MS

Message
*Order Cortisol Free, 24-Hour Urine for a Cortisol Free, Random Urine. Must note that we are submitting a random urine instead of 24-hour urine.


Test Code
11280


Alias/See Also
LAB382
CORTF 24UR 24 HOUR HR URINE


CPT Codes
82530

Includes
CPT code 81050 may be added at an additional charge for volume measurement


Preferred Specimen
2 mL urine from a 24-hour collection (no preservatives)


Minimum Volume
0.5 mL


Other Acceptable Specimens
25 mL 6N HCl • 10 mL concentrated glacial acetic acid • 10 g boric acid


Instructions
Record 24-hour urine volume on test requisition and urine vial. Reference ranges do not apply to random urine samples.


Transport Container
Transport tube


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 90 days


Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Mon-fri


Report Available
2-6 days


Reference Range
Cortisol, Free, 24-Hr Urine
 Adult 4.0-50.0
 Pediatric  
   1-4 Years 0.9-8.2 mcg/24 hrs
   5-9 Years 1.0-30.0 mcg/24 hrs
   10-13 Years 1.0-45.0 mcg/24 hrs
   14-17 Years 3.0-55.0 mcg/24 hrs

Creatinine, 24-Hour Urine
<3 Years Not established
3-8 Years 0.10-0.80 g/24 hours
9-12 Years 0.20-1.40 g/24 hours
13-17 Years 0.40-1.90 g/24 hours
>17 Years 0.50-2.15 g/24 hours


Clinical Significance
Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.