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Parietal Cell Antibody, ELISA
Test Code15114
Alias/See Also
LAB514
GASTRIC PARIETAL CELL ANTIBODY
GASTRIC PARIETAL CELL ANTIBODY
CPT Codes
83516
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Received room temperature
Methodology
Immunoassay (IA)
Setup Schedule
Tuesday, thursday, saturday
Report Available
2-6 days
Reference Range
| ≤20.0 U | Negative | |
| 20.1-24.9 U | Equivocal | |
| ≥25.0 U | Positive | |
Clinical Significance
Gastric Parietal Cell Antibodies are found in 90% of patients with pernicious anemia. They are also found in autoimmune chronic atrophic gastritis preceding pernicious anemia. The antigenic target is the H+/K+ ATPase gastric proton pump responsible for parietal cell acid generation in the stomach.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |