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Neisseria meningitidis, IgG, Vaccine Response, MAID
Test Code15903
Alias/See Also
LAB1254
MAID
GC IgG
MAID
GC IgG
CPT Codes
86317 (x4)
Includes
Serotypes A, C, Y, W-135
Preferred Specimen
0.5 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Multi-Analyte Immunodetection (MAID)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Tues
Report Available
1-7 days
Reference Range
Serogroup A | <4.0 ug/mL |
Serogroup C | <5.0 ug/mL |
Serogroup Y | <4.0 ug/mL |
Serogroup W-135 | <3.0 ug/mL |
Clinical Significance
This assay measures serum IgG antibodies recognizing polysaccharide antigens from the four Neisseria meningitidis serogroups included in the licensed meningococcal vaccine. The meningococcal vaccine response is best evaluated by testing pre-vaccination and post-vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing post-vaccination to pre-vaccination results. N. Meningitidis IgG levels peak approximately one month post-vaccination, but decline markedly by two years.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |