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Inflammatory Bowel Disease Differentiation Panel
Test Code16503
Alias/See Also
LAB1230
CPT Codes
86021 (x2), 86036, 86671 (x2)
Includes
ANCA Screen with Reflex to ANCA Titer
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
Saccharomyces cerevisiae Antibodies (ASCA) (IgG)
Saccharomyces cerevisiae Antibodies (ASCA) (IgA)
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
Saccharomyces cerevisiae Antibodies (ASCA) (IgG)
Saccharomyces cerevisiae Antibodies (ASCA) (IgA)
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Preferred Specimen
2 mL serum
Minimum Volume
1.4 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Grossly icteric
Methodology
Immunoassay (IA)
Reference Range
ANCA Screen | Negative |
P-ANCA Titer | <1:20 |
C-ANCA Titer | <1:20 |
Atypical P-ANCA Titer | <1:20 |
Myeloperoxidase Antibody
<1.0 AI | No antibody detected |
≥1.0 AI | Antibody detected |
Proteinase-3 Antibody
<1.0 AI | No antibody detected |
≥1.0 AI | Antibody detected |
Saccharomyces cerevisiae Ab (IgG)
≤20.0 U | Negative |
20.1-29.9 U | Equivocal |
≥30.0 U | Positive |
Saccharomyces cerevisiae Ab (IgA)
≤20.0 U | Negative |
20.1-24.9 U | Equivocal |
≥25.0 U | Positive |
Clinical Significance
This panel is useful in the diagnosis of Inflammatory Bowel diseases and can help to distinguish patients with ulcerative colitis from those with Crohn's Disease.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |