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Saccharomyces cerevisiae Antibodies (ASCA) (IgG, IgA)
Test Code17609
Alias/See Also
LAB548
ASCA G/A
ASCA G/A
CPT Codes
86671 (x2)
Preferred Specimen
2 mL serum
Minimum Volume
0.6 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 21 days
Refrigerated: 21 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia
Methodology
Immunoassay (IA)
Reference Range
Saccharomyces cerevisiae Ab (ASCA) (IgG)
Saccharomyces cerevisiae Ab (ASCA) (IgA)
| ≤20.0 U | Negative |
| 20.1-29.9 U | Equivocal |
| ≥30.0 U | Positive |
Saccharomyces cerevisiae Ab (ASCA) (IgA)
| ≤20.0 U | Negative |
| 20.1-24.9 U | Equivocal |
| ≥25.0 U | Positive |
Clinical Significance
Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |