Varicella-Zoster Virus DNA, Quantitative Real-Time PCR

Test Code
19493


CPT Codes
87799<br><strong>This test is not available for New York patient testing at Quest Diagnostics Nichols Institute-San Juan Capistrano, CA.</strong><br><strong>Orders for New York patients will be redirected to Quest Diagnostics Nichols Institute-Chantilly, VA for testing.</strong>

Preferred Specimen
1 mL whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube or
1 mL CSF, collected in a sterile, plastic, leak-proof container or
1 mL bronchial wash/brush collected in a sterile, plastic, leak-proof container


Minimum Volume
0.3 mL


Transport Container
EDTA (lavender-top) tube or ACD (yellow-top) tube or
Sterile plastic leak-proof container


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Whole blood
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: Unacceptable

All other samples
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Heparin whole blood


Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

This test is not available for New York patient testing at Quest Diagnostics Nichols Institute-San Juan Capistrano, CA.
Orders for New York patients will be redirected to Quest Diagnostics Nichols Institute-Chantilly, VA for testing.

Setup Schedule
Daily


Report Available
2-4 days


Reference Range

Not Detected



Clinical Significance
Varicella-Zoster virus (VZV) is a member of the Herpesviridae family that causes chickenpox as a primary infection and can reactivate later in life as herpes zoster or shingles. VZV infection in immunocompromised individuals often leads to a progressive disease state involving multiple organs. The detection of Varicella-Zoster Virus (VZV) DNA is based upon the real-time amplification and detection of specific VZV genomic DNA sequences by PCR from total DNA extracted from the specimen.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.