| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
JC Polyoma Virus DNA, Quantitative Real-Time PCR, Serum/Plasma
Test Code19503
Alias/See Also
LAB00228
CPT Codes
87799
Preferred Specimen
0.7 mL plasma collected in an EDTA (lavender-top), ACD (yellow-top) or PPT (white-top) tube or
0.7 mL serum
0.7 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
CSF • Urine
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Daily
Report Available
2-3 days
Reference Range
| JC Virus DNA, QN PCR | Not Detected (IU/mL) |
| JC Virus DNA, QN PCR | Not Detected (Log IU/mL) |
Clinical Significance
JC Polyoma Virus is the cause of Progressive Multifocal Leukoencephalopathy (PML), a severe demyelinating disease of the central nervous system. PML is a particular concern for individuals infected with the human immunodeficiency virus. Quantification of JC virus DNA is based upon the real-time PCR amplification and detection of JCV genomic DNA. Reportable range is 50 to 50,000,000 IU/mL (1.70 to 7.70 Log IU/mL).
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |