TSH with HAMA Treatment

Test Code

19537

Alias/See Also

LAB00329
THYROID STIMULATION HORMONE , TSH HAMA TREATMENT
TSH W/HAMA TREATMENT

CPT Codes
84443 (x2)

Includes

Ultrasensitive TSH with and without HAMA treatment

Preferred Specimen

2 mL serum collected in a red-top tube (no gel)

Patient Preparation
Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay. "

Minimum Volume

1.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days

Methodology
Immunoassay (IA)

Setup Schedule

Tues-sat

Report Available

2-3 days

Reference Range

TSH, HAMA Treated	See below
TSH, Untreated
Premature infant (28-36 weeks), 1st week of life	0.20-27.90 mIU/L
Term infant (>37 Weeks), serum or cord blood	1.00-39.00 mIU/L
1-2 Days	3.20-34.60 mIU/L
3-4 Days	0.7-15.40 mIU/L
5 Days-4 Weeks	1.70-9.10 mIU/L
1-11 Months	0.80-8.20 mIU/L
1-19 Years	0.50-4.30 mIU/L
≥20 Years	0.40-4.50 mIU/L
Pregnancy
First Trimester	0.26-2.66 mIU/L
Second Trimester	0.55-2.73 mIU/L
Third Trimester	0.43-2.91 mIU/L

Clinical Significance

Precision in the estimation of TSH is crucial to the follow-up of subjects with thyroid disorders. The preincubation of samples to remove HAMA immunoglobulins provides a way to ensure that an otherwise unsuspected rise or drop in TSH concentration will not be interpreted as either a false positive or false negative.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.