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IGF Binding Protein-1 (IGFBP-1)
Test Code36590
Alias/See Also
LAB00219
CPT Codes
83519
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.2 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Plasma • Received room temperature
Methodology
Radioimmunoassay (RIA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Tues
Report Available
3-9 days
Reference Range
Adults | 5-34 ng/mL | |
Pediatric | ||
5-9 Years | 15-95 ng/mL | |
10-14 Years | 8-64 ng/mL | |
15-18 Years | 5-40 ng/mL |
Clinical Significance
The concentration of IGFBP-1 is correlated with glycemic conditions. IGFBP-1 may be used for monitoring insulin responsiveness, as a marker for insulin-producing tumors, monitoring acute fluctuations in insulin action, and determining if poor glycemic control is due to inadequate insulin treatment or poor control of dietary intake.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |