Porphyrins, Fractionated, Quantitative, Random Urine

Message

*Protect from light.

Test Code

36592

Alias/See Also

LAB433

CPT Codes
84120

Includes

Coproporphyrin I, Coproporphyrin III, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Uroporphyrin I, Uroporphyrin III, Total Porphyrins

Preferred Specimen

2 mL random urine in 5 g sodium carbonate container or no preservative container - protected from light

Minimum Volume

1.5 mL

Other Acceptable Specimens

Random clean catch urine • Catheterized urine • First void clean catch • Random urine collected with sodium bicarbonate • Random urine collected with no preservatives
(ok to add preservative after collection)

Instructions

Random urine collected with 5 grams of sodium carbonate, refrigerated and protected from light during collection is preferred.
Collection with no preservative is acceptable, if properly refrigerated and light protected.

Transport Container

Sodium carbonate container

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Samples not protected from light • Samples with a pH <4.0

Methodology
High Performance Liquid Chromatography (HPLC)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Sun, tues-fri

Report Available

5-7 days

Reference Range

Uroporphyrin I	3.6-21.1 mcg/g creat
Uroporphyrin III	≤5.6 mcg/g creat
Heptacarboxyporphyrin	≤3.4 mcg/g creat
Hexacarboxyporphyrin	≤6.3 mcg/g creat
Pentacarboxyporphyrin	≤4.1 mcg/g creat
Coproporphyrin I	6.5-33.2 mcg/g creat
Coproporphyrin III	4.8-88.6 mcg/g creat
Total Porphyrins	27.0-153.6 mcg/g creat

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.