Ganglioside GM-1 Antibodies (IgG, IgM), EIA

Test Code

37093

CPT Codes
83520 (x2)

Preferred Specimen

1 mL serum

Patient Preparation
Overnight fasting is preferred

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature

Methodology
Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Mon, wed

Report Available

4-9 days

Reference Range

GM-1 Antibody (IgG)	<1:800 titer
GM-1 Antibody (IgM)	<1:800 titer

IgG, IgM Antibodies to Ganglioside GM1

Normal	<1:800
Moderately elevated	1:800-1:3200
Highly elevated	≥1:6400

Clinical Significance

Ganglioside GM-1 Antibody IgG is associated with the Guillain-Barre syndrome, particularly the acute motor axonal neuropathy variant. Antibody IgM is associated with chronic multifocal motor neuropathy.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.