| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Coxsackie A Antibodies, Serum
Test Code37477
Alias/See Also
LAB00881
COXA ABS
COX A
COXA ABS
COX A
CPT Codes
86317 (x6)
Includes
Coxsackie Antibodies A2, A4, A7, A9, A10, A16
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Complement Fixation (CF)
Setup Schedule
Tues-sat
Report Available
3-5 days
Limitations
Culture does not usually support growth of coxsackie A viruses.
Reference Range
| Coxsackie A2 Ab | <1:8 titer |
| Coxsackie A4 Ab | <1:8 titer |
| Coxsackie A7 Ab | <1:8 titer |
| Coxsackie A9 Ab | <1:8 titer |
| Coxsackie A10 Ab | <1:8 titer |
| Coxsackie A16 Ab | <1:8 titer |
Interpretive Criteria
| <1:8 | Antibody Not Detected |
| ≥1:8 | Antibody Detected |
Clinical Significance
Panel currently includes testing against A-2, 4, 7, 9, 10, and 16 antigens. Although there is cross-reactivity among the enteroviruses by CF, most healthy people do not have titers >1:8. Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |