Rickettsia Antibody Panel with Reflex to Titers

Test Code

37507

Alias/See Also

LAB1264
RMSF
ROCKY MOUNTAIN SPOTTED FEVER
RICKETTSIA
THYPHUS FEVER

CPT Codes
86757 (x4)

Includes

Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers
Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers

If Rickettsia (RMSF) screen is Detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).
If Rickettsia (Typhus Fever) screen is Detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology
Immunofluorescent Assay (IFA)

Limitations

Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.

Reference Range

	Screen	Titer
RMSF IgG	Not detected	<1:64
RMSF IgM	Not detected	<1:64
R. typhi IgG	Not detected	<1:64
R. typhi IgM	Not detected	<1:64

Clinical Significance

Antigen-specific IgG and IgM titers allow rapid diagnosis of infection by organisms within either of the two major groups of Rickettsia. The spotted fever group includes R. rickettsia (Rocky Mountain Spotted Fever) and R. akari (Rickettsial pox). The typhus group includes R. typhi (endemic/murine typhus) and R. prowazeki (epidemic typhus).

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.