TRAb (TSH Receptor Binding Antibody)

Test Code

38683

Alias/See Also

LAB574
TRAB
THYROTROPIN BINDING
THYROTROPIN RECEPTOR AB

CPT Codes
83520

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Allow serum to clot at room temperature. Serum must be separated from the cells or gel barrier within 1 hour of collection and poured into a transport vial.

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Serum received in a gel barrier tube or on the cells

Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

Setup Schedule

Tues, thurs, sat

Report Available

3-5 days

Reference Range

≤2.00 IU/L

Clinical Significance

Measurement of TRAb is used to diagnose and manage Graves' disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.