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Adenosine Deaminase, RBC
Test Code39148
Alias/See Also
LAB00480
CPT Codes
82657<br /> <strong>This test is not available for New York patient testing.</strong>
Preferred Specimen
1 mL whole blood collected in an EDTA (lavender-top or pink-top) or sodium or lithium heparin (green top) tube
Minimum Volume
1 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 15 days
Refrigerated: 15 days
Frozen: Unacceptable
Refrigerated: 15 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Kinetic Spectrophotometry
FDA Status
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical; diagnosis or patient management decisions.
This test is not available for New York patient testing.
Setup Schedule
Sun, tues, thurs
Report Available
2-6 days
Reference Range
400-900 mU/g Hb
Clinical Significance
Adenosine Deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism primarily affecting lymphocyte development, viability, and function. Affected individuals have less than 1 percent of normal ADA catalytic activity in red cell hemolysates. ADA deficiency is the cause of 20-30 percent of SCID cases. If the patient has been recently transfused, ADA deficiency may be masked; interpret results with caution. Heterozygotes cannot be identified by this test.
Performing Laboratory
| A.R.U.P. , Inc. |
| 500 Chipeta Way |
| Salt Lake City, UT 84108-1221 |