Histamine, 24-Hour Urine

Test Code

4946

Alias/See Also

LAB00191

CPT Codes
83088

Includes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen

4 mL urine from a 24-hour urine containing 10 mL 6N HCL collected in a leak-proof container

Patient Preparation
Avoid direct sunlight. Patient should refrain from taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection.

Minimum Volume

2 mL

Other Acceptable Specimens

Non-preservative 24-hour urine collected in a leak-proof container

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 14 days

Methodology
Immunoassay (IA)

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

Tues, fri

Report Available

2-7 days

Reference Range

0.006-0.131 mg/24 h

Clinical Significance

Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.