Tacrolimus, Highly Sensitive, LC/MS/MS

Message
WHOLE BLOOD - DO NOT CENTRIFUGE


Test Code
70007


Alias/See Also
LAB876
TACROLIMUS
FK506
PROGRAF


CPT Codes
80197

Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube


Patient Preparation
Collect specimen 1 hour prior to next dose (12 hour trough)

Minimum Volume
1 mL


Transport Container
EDTA (lavender-top) tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 60 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
10: 00 a. M. Mon-sat


Report Available
1-2 days


Reference Range
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation.
The following trough range is a suggested guideline: 5.0-20.0 mcg/L


Clinical Significance
Tacrolimus is an immunosuppressant drug which has been shown to be effective for the treatment of rejection following transplantation.


Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.