| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
ANCA Screen with MPO and PR3, with Reflex to ANCA Titer
Test Code70159
Alias/See Also
LAB00196
CPT Codes
86021 (x2), 86036
Includes
ANCA Screen with Reflex to ANCA Titer
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Preferred Specimen
2 mL serum
Minimum Volume
0.8 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Reference Range
| ANCA Screen | Negative |
| P-ANCA Titer | <1:20 |
| C-ANCA Titer | <1:20 |
| Atypical P-ANCA Titer | <1:20 |
Myeloperoxidase Antibody
| <1.0 AI | No antibody detected |
| ≥1.0 AI | Antibody detected |
Proteinase-3 Antibody
| <1.0 AI | No antibody detected |
| ≥1.0 AI | Antibody detected |
Clinical Significance
Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases, inflammatory bowel disease, as well as other autoimmune diseases.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |