Hydrocodone and Metabolite, Serum

Test Code
90489


Alias/See Also
LAB00214
 


CPT Codes
80361 (HCPCS: G0480)

Includes
Hydrocodone, Free and Hydromorphone, Free


Preferred Specimen
5 mL serum collected in a red-top tube (no gel)


Minimum Volume
2.5 mL


Transport Container
Transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 14 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
10: 00 a. M. Tues, sat


Report Available
2-4 days


Reference Range
Hydrocodone, Free 5.0-24.0 ng/mL
Hydromorphone, Free 5.0-30.0 ng/mL


Clinical Significance
Therapeutic drug monitoring and confirmation of screen- positive results. Hydrocodone is an active component of Vicodin®, Lorcet®, Lortab®, etc. Serum half-life is 3.4 to 8.8 hours. Hydromorphone is an active ingredient in Dilaudid®. Serum half-life is 1.5 to 3.8 hours.


Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.