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von Willebrand Panel
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CENTRIFGUE AND FREEZE PLASMA IMMEDIATELY.
CENTRIFGUE AND FREEZE PLASMA IMMEDIATELY.
Test Code
91242
Alias/See Also
LAB1112
VFW PNL
VFW PNL
CPT Codes
85240, 85246, 85245, 85730
Includes
Factor VIII Activity, Clotting
von Willebrand Factor Antigen
Ristocetin Cofactor
Partial Thromboplastin Time, Activated
von Willebrand Factor Antigen
Ristocetin Cofactor
Partial Thromboplastin Time, Activated
Preferred Specimen
3.6 mL platelet-poor plasma collected in 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1.8 mL
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Refrigerated: Unacceptable
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia
Methodology
Immunoturbidimetric Assay • Photometric Clot Detection • Photo-Optical Clot Detection • Platelet Agglutination
Reference Range
See individual tests
Clinical Significance
von Willebrand disease is the most common bleeding disorder. The diagnosis can only be assured by performing a multiplicity of tests to confirm the diagnosis, and to distinguish type 1, type 2, and type 3 disease types which require different treatment programs. It is essential to measure FVIII activity along with vWF Antigen, Functional vWF Activity by Ristocetin Cofactor and measure Multimeric analysis of von Willebrand Protein to characterize intermediate and high weight forms.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |