von Willebrand Panel

Message

*Take to processing ASAP.
CENTRIFGUE AND FREEZE PLASMA IMMEDIATELY.

Test Code

91242

Alias/See Also

LAB1112
VFW PNL

CPT Codes
85240, 85246, 85245, 85730

Includes

Factor VIII Activity, Clotting
von Willebrand Factor Antigen
Ristocetin Cofactor
Partial Thromboplastin Time, Activated

Preferred Specimen

3.6 mL platelet-poor plasma collected in 3.2% sodium citrate (light blue-top) tube

Minimum Volume

1.8 mL

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lipemia

Methodology
Immunoturbidimetric Assay • Photometric Clot Detection • Photo-Optical Clot Detection • Platelet Agglutination

Reference Range

See individual tests

Clinical Significance

von Willebrand disease is the most common bleeding disorder. The diagnosis can only be assured by performing a multiplicity of tests to confirm the diagnosis, and to distinguish type 1, type 2, and type 3 disease types which require different treatment programs. It is essential to measure FVIII activity along with vWF Antigen, Functional vWF Activity by Ristocetin Cofactor and measure Multimeric analysis of von Willebrand Protein to characterize intermediate and high weight forms.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.