14.3.3 eta Protein

Test Code

91455

CPT Codes
83520

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 1 year

Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Mon-thurs

Report Available

3-7 days

Reference Range

<0.2 ng/mL

Clinical Significance

The 14-3-3η protein appears to contribute to the pathologic process of joint erosion and, as such, is an emerging biomarker of joint damage in rheumatoid arthritis (RA) and psoriatic arthritis. Concentrations are significantly higher in people with active joint disease than in those with inactive RA or psoriasis without arthritis. Measurement of 14-3-3η complements RF and CCP antibody tests and may improve diagnostic sensitivity.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.