Leishmania Antibody (IgG)

Test Code

92480

Alias/See Also

LAB1248
KALAZAR
VISCERAL LEISHMANIASIS

CPT Codes
86717

Preferred Specimen

0.2 mL serum

Minimum Volume

0.1 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology
Enzyme Immunoassay (EIA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Wed

Report Available

1-7 days

Reference Range

<1.00

Interpretive Criteria

<1.00	Negative
≥1.00	Positive

This assay is intended to aid in the diagnosis of visceral leishmaniasis. Its use in diagnosing cutaneous leishmaniasis is limited, since a detectable antibody response is often absent in this form of the disease. Sera from patients with Chagas' disease (Trypanosoma cruzi infection) may be positive in this assay; thus, results should be used in conjunction with other clinical findings when considering a diagnosis of leishmaniasis.

Clinical Significance

Detection of Leishmania IgG provides strong support for the diagnosis of visceral leishmaniasis. Some (but not all) patients with cutaneous leishmaniasis also have detectable serum levels of Leishmania IgG. Sera from patients with Trypanosoma cruzi infection (Chagas' disease) show significant cross-reactivity in the Leishmania IgG assay.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.