Vitamin B12 (Cobalamin)

Test Code

CPT Codes

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Other Acceptable Specimens
Amber vial

Transport Container
Serum Separator Tube (SST®)

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Rrefrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)


Immunoassay (IA)

Setup Schedule
6: 00 a. M. , 10: 00 a. M. , 2: 00 p. M. , 6: 00 p. M. Tues-sat

Report Available
1-3 days

Reference Range
≤4 Years Not established
5-9 Years 250-1205 pg/mL
10-17 Years 260-935 pg/mL
>17 Years 200-1100 pg/mL

Clinical Significance
B12 is decreased in pernicious anemia, total or partial gastrectomy, malabsorption and certain congenital and biochemical disorders.

Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.