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Beta-Amyloid 42/40 Ratio and Apolipoprotein E (APOE) Isoform Panel, CSF
Test Code94628
Alias/See Also
LAB00380
CPT Codes
82542 (x2), 82172<br /> <strong>This test is not available for New York patient testing.</strong>
Preferred Specimen
1.6 mL CSF
Minimum Volume
0.8 mL
Instructions
Collect and transport CSF in a 12x75 mm polypropylene tube. Store frozen.
Note: Quest Diagnostics does not perform this test for individuals under the age of 18. Pre-test and post-test counseling is strongly recommended.
Transport Container
Polypropylene tube
Transport Temperature
Frozen
Specimen Stability
Room tempurature: 72 hours
Refrigerated: 5 days
Frozen: 31 days
Refrigerated: 5 days
Frozen: 31 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Grossly lipemic • Specimen collected in a glass, polystyrene, or polycarbonate tube • Moderately and grossly icteric
Methodology
Liquid Chromotography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics . It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
This test is not available for New York patient testing.
Setup Schedule
Sun
Report Available
5-12 days
Reference Range
See Laboratory Report
Clinical Significance
This panel of LC/MS/MS assays measures Beta-Amyloid 42/40 Ratio and ApoE Isoform and Total ApoE in CSF. Test results are further analyzed by an algorithm that calculates a risk assessment score. Based on this score, patients are categorized as low, intermediate, or high risk of having AD.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |