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HUMAN PLACENTAL LACTOGEN
MessageSee Carrie or Amber to obtain Wild Code from Quest.
NOTE: Sex and, if pregnant, the gestation period must be included with the requisition.
*Take to processing ASAP.
NOTE: Sex and, if pregnant, the gestation period must be included with the requisition.
*Take to processing ASAP.
Test Code
LAB1041
Alias/See Also
LAB1041
Placental Lactogen
Placental Lactogen
CPT Codes
83632
Preferred Specimen
1.0 mL Serum
Marble/Gold/Red Top
Marble/Gold/Red Top
Minimum Volume
0.5 mL Serum
Instructions
Allow blood to clot for 30 minutes. Centrifuge at 3000 rpm for 10 minutes. Separate serum and place in a transfer tube. Freeze immediately at -20oC.
Transport Temperature
Frozen
Specimen Stability
Frozen: 90 days
Methodology
ELISA
Report Available
Up to 7 business days
Reference Range
Men and Non-Pregnant Women: 0 - 0.1 mcg/mL
1st Trimester of Pregnancy: 0.2 - 2.1 mcg/mL
2nd Trimester of Pregnancy: 0.5 – 6.7 mcg/mL
3rd Trimester of Pregnancy: 4.5 – 12.8 mcg/mL
1st Trimester of Pregnancy: 0.2 - 2.1 mcg/mL
2nd Trimester of Pregnancy: 0.5 – 6.7 mcg/mL
3rd Trimester of Pregnancy: 4.5 – 12.8 mcg/mL
Clinical Significance
Human placental lactogen (hPL; chorionic somatomammotropin) is a 21,000 KD polypeptide produced during pregnancy by placental trophoblastic cells. The level of hPL in maternal serum is directly related to placental function and fetal well-being. hPL is detected at about 6 weeks after conception and its concentration increases gradually to peak levels (without decreases) until about the 34th week where it remains stable for the remainder of the pregnancy. Consistently low levels throughout pregnancy or a sudden drop in serial determinations are an indication of fetal distress. After normal delivery, the hPL concentration falls rapidly to an undetectable level. The hPL levels in serum of women with multiple placenta pregnancies generally exceeds that of single placenta pregnancies. This is generally noted from the 2nd trimester to delivery.
Performing Laboratory
Sent by Quest to:
Cambridge Biomedical Inc.
1320 Soldiers Field Road
Boston, MA 02135
www.cambridgebiomedical.com