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HIV GENOSURE ARCHIVE DNA SEQUENCING
MessageQUEST WILDCODE NEEDED.
Call Carrie x4171 or Amber x4173
SPECIMEN REQUIRES FROZEN EDTA WHOLE BLOOD.
Call Carrie x4171 or Amber x4173
SPECIMEN REQUIRES FROZEN EDTA WHOLE BLOOD.
Test Code
LAB00368
Alias/See Also
LAB00368
CPT Codes
87900,87901,87906
Preferred Specimen
4mL Lavender (EDTA) - Whole Blood
Freeze Immediately
Freeze Immediately
Minimum Volume
1 mL Lavender (EDTA)
Instructions
Draw whole blood in 1 lavender top(EDTA) tube. Do not centrifuge.FREEZE IMMEDIATELY AT -20c AND SHIP FROZEN.
Clinical Significance
GenoSure Archive is designed to provide HIV-1 antiretroviral (ARV) drug resistance data when standard resistance testing cannot be performed due to inadequate plasma viral load. The assay interrogates the viral archive using next-generation sequencing (NGS) methods to provide a list of the archived mutations and then assigns susceptibility calls of "sensitive," "resistant," or "resistance possible" based on those mutations.
GenoSure Archive provides valuable information for nucleoside reverse transcriptase inhibitors (NRTIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs), integrase inhibitors (INIs) and protease inhibitors (PIs) when considering regimen switches in virologically suppressed patients .
Performing Laboratory
Send to Quest Diagnostics, they will send onto Monogram Biosciences