A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
NEUROTENSIN
MessageREQUIRES QUEST WILDCODE.
Call Carrie x4171 or Amber x4173
Call Carrie x4171 or Amber x4173
*Collect in special Z-tube - Call Processing, tube is in processing refrigerator*
Test Code
LAB00255
Alias/See Also
LAB00255
Z-tube Preservative needed from Inter Science Institute.
Z-tube Preservative needed from Inter Science Institute.
CPT Codes
83519
Preferred Specimen
Collect special 10 mL Z-tube (processing refrigerator) - Bring to processing ASAP
Patient Preparation
Patient should be fasting 10-12 hours before specimen collection. Patient should not be on any antacid medication or medications that affect gasteroenterointestinal function, if possible, for at least 48 hours before specimen collection.
Instructions
Collect 10 mL of blood directly into a Z-tube - Tube does not clot!
Bring to processing ASAP. Processing needs to separate plasma as soon as possible.
Freeze plasma immediately after separation.
Special Z-tube is requested from Quest Diagnostics.
Bring to processing ASAP. Processing needs to separate plasma as soon as possible.
Freeze plasma immediately after separation.
Special Z-tube is requested from Quest Diagnostics.
Transport Temperature
Frozen
Specimen Stability
Frozen: 1 Month
Methodology
Direct radioimmunoassay
Reference Range
Neurotensin:
50-100 pg/ml
50-100 pg/ml
Clinical Significance
Neurotensin is a 13-amino acid peptide, produced primarily by endocrine cells of the ileal mucosa. Physiological actions of Neurotensin include hypertension, vasodilation, hyperglycemia, and inhibition of gastric motility. Its C-terminus is similar to Angiotensin I. It is a potent analgesic affecting hypothermia, muscle relaxation, and decreased motor activity. Pancreatic Polypeptide secretion is strongly stimulated by Neurotensin. Neurotensin appears to cause the release of Luteinizing Hormone-Releasing Hormone and Corticotropin Releasing Hormone, effecting the release of Luteinizing Hormone, Follicle Stimulatng Hormone, and ACTH, but not Thyroid Stimulatng Hormone or Growth Hormone. Neurotensin also stimulates pancreatic bicarbonate and intestinal secretion. Neurotensin levels are stimulated by food and Bombesin. Elevated levels have been found in pancreatic endocrine tumors, Oat Cell, Squamous, and Adenocarcinomas. Elevated levels have been found to cause watery diarrhea.
Performing Laboratory
Send to Quest Diagnostics, they send onto Inter-Science Institute