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Autoimmune Cerebellar Ataxia Panel
MessageRequires Quest WildCode.
Call Carrie x4171 or Amber x4173
Call Carrie x4171 or Amber x4173
Test Code
LAB00880
Alias/See Also
LAB00880
ATAXIA PANEL
AUTOIMMUNE CEREBELLAR ATAXIA PANEL
SP-ATAXIA PANEL
Quest TC: 90133
ATAXIA PANEL
AUTOIMMUNE CEREBELLAR ATAXIA PANEL
SP-ATAXIA PANEL
Quest TC: 90133
CPT Codes
82784, 83516, 83519, 86255
Includes
Includes Yo Antibody Screen with Reflex to Titer and Western Blot Voltage-Gated Calcium Channel (VGCC) Type P/Q Antibody Tissue Transglutaminase (tTG) Antibody (IgA) IgA (Immunoglobulin A) If Yo Antibody Screen, IFA is positive, then Yo Antibody, Western Blot will be performed at an additional charge (CPT code(s): 84181). If Yo Antibody, Western Blot is positive, then Yo Antibody, Titer will be performed at an additional charge (CPT code(s): 86256). If Tissue Transglutaminase (tTG) Antibody (IgA) is positive (>8), then Endomysial Antibody Screen (IgA) will be performed at an additional charge (CPT code(s): 86255). If Endomysial Antibody Screen (IgA) is positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86256). If Immunoglobulin A is abnormal, then Tissue Transglutaminase (tTG) Antibody (IgG) will be performed at an additional charge (CPT code(s): 83516).
Preferred Specimen
3 mL Serum Red Top (No Gel)
Patient Preparation
Overnight fasting is preferred
Minimum Volume
1.3 mL Serum Red Top (No Gel)
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 7 days
Methodology
Immunoassay (IA) • Immunofluorescence Assay (IFA) • Immunoturbidometry • Radiobinding Assay (RBA)
Clinical Significance
Cerebellar ataxia may occur as a result of autoantibodies to cerebellar targets. These may include antibodies to the Purkinje cell antigen Yo, the voltage gated calcium channel (VGCC) or tissue transglutaminase (tTG). Glutin ataxia is associated with widespread tissue transglutaminase (tTG) IgA deposition around vessels in the cerebellum, pons, and medulla.
Performing Laboratory
Quest Diagnostics Nichols Institute