Autoimmune Cerebellar Ataxia Panel

Message

Requires Quest WildCode.
Call Carrie x4171 or Amber x4173

Test Code

LAB00880

Alias/See Also

LAB00880
ATAXIA PANEL
AUTOIMMUNE CEREBELLAR ATAXIA PANEL
SP-ATAXIA PANEL
Quest TC: 90133

CPT Codes
82784, 83516, 83519, 86255

Includes

Includes Yo Antibody Screen with Reflex to Titer and Western Blot Voltage-Gated Calcium Channel (VGCC) Type P/Q Antibody Tissue Transglutaminase (tTG) Antibody (IgA) IgA (Immunoglobulin A) If Yo Antibody Screen, IFA is positive, then Yo Antibody, Western Blot will be performed at an additional charge (CPT code(s): 84181). If Yo Antibody, Western Blot is positive, then Yo Antibody, Titer will be performed at an additional charge (CPT code(s): 86256). If Tissue Transglutaminase (tTG) Antibody (IgA) is positive (>8), then Endomysial Antibody Screen (IgA) will be performed at an additional charge (CPT code(s): 86255). If Endomysial Antibody Screen (IgA) is positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86256). If Immunoglobulin A is abnormal, then Tissue Transglutaminase (tTG) Antibody (IgG) will be performed at an additional charge (CPT code(s): 83516).

Preferred Specimen

3 mL Serum Red Top (No Gel)

Patient Preparation
Overnight fasting is preferred

Minimum Volume

1.3 mL Serum Red Top (No Gel)

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated: 7 days

Methodology
Immunoassay (IA) • Immunofluorescence Assay (IFA) • Immunoturbidometry • Radiobinding Assay (RBA)

Clinical Significance

Cerebellar ataxia may occur as a result of autoantibodies to cerebellar targets. These may include antibodies to the Purkinje cell antigen Yo, the voltage gated calcium channel (VGCC) or tissue transglutaminase (tTG). Glutin ataxia is associated with widespread tissue transglutaminase (tTG) IgA deposition around vessels in the cerebellum, pons, and medulla.

Performing Laboratory
Quest Diagnostics Nichols Institute

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.