Paroxysmal Nocturnal Hemoglobinuria (PNH)

Message
*Collect specimen Monday through Friday only before 1500 EST. Do not collect the day before a holiday.


Test Code
LAB928


Alias/See Also
Paroxysmal Nocturnal Hemoglobinuria (PNH) LABCORP TEST: 502251
LAB928
CD55-CD59


CPT Codes
88184,88158,88187

Preferred Specimen
Green-top (sodium heparin) tube (preferred) or lavender-top (EDTA) tube
NOTE: Draw Monday through Thursday ONLY. Specimens must arrive at Integrated Oncology within 48 hous of collection.


Minimum Volume
5 mL


Instructions
Collect Monday through Thursday only. Specimens must arrive at Integrated Oncology—Brentwood or Phoenix—within 48 hours of collection.


Transport Temperature
Ambient


Specimen Stability
72 hrs. ambient


Methodology
Flow Cytometry

Limitations
Samples with <1000 WBC/μL may only have RBC analysis reported


Clinical Significance
The following markers are utilized to test neutrophils and/or monocytes: CD24, CD15, CD45, FLAER, CD64, CD14. If a PNH clone is identified, the following markers are used to test red blood cells: glycophorin A, CD59.


Performing Laboratory
LABCORP



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.