Chronic Lymphocytic Leukemia (CLL), FISH

Test Code
LAB937


Alias/See Also
LAB937
LabCorp TC: 510340
CLL


CPT Codes
88271, 88275

Preferred Specimen
Adult: 10mL Lavender (EDTA) - Whole Blood - 2 full tubes
Ped: 3-5 mL Lavender (EDTA) - Whole Blood - 1 full tube


Minimum Volume
1 mL
 


Other Acceptable Specimens
Dark Green Top (Sodium Heparin)
 


Transport Temperature
Room Temperature


Specimen Stability
Sample quality will be determined by testing facility. It is best for specimens to ship the same day as collected.


Methodology
Fluorescence in situ hybridization (FISH) 

Report Available
3-5 days


Limitations
Molecular mutations below the resolution of FISH will not be detected. 
This test is developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.


Clinical Significance
Diagnostic and prognostic test for chronic lymphocytic leukemia; detection rate is improved from 45% with a chromosome study to 80% with fluorescence in situ hybridization (FISH). Differentiates CLL from MCL.


Performing Laboratory
LABCORP



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.