FISH, Oncology

Message

Pertinent clinical diagnosis, previous cytogenetic studies, and probe of interest should be included with the specimen. This test number is used for tracking oncology FISH specimens to the laboratory. Please provide targeted FISH probe and diagnosis. The test will only be performed after the probes and diagnosis is provided. Absence of this information will delay turnaround time.

Test Code

LAB2352

Alias/See Also

LAB2352
LabCorp TC: 510669
LabCorp: Fluorescence in situ Hybridization (FISH), Oncology
t(14;18) translocation

CPT Codes
88271

Preferred Specimen

Adult: 10 mL Dark Green Top (Sodium Heparin) - Whole Blood - 2 full tubes
Ped: 5 mL Dark Green Top (Sodium Heparin) - Whole Blood - 1 full tube
3 mL bone marrow

Minimum Volume

Adult: 5 mL Dark Green Top (Sodium Heparin)
Ped: 1 mL Dark Green Top (Sodium Heparin)

Other Acceptable Specimens

Lavender (EDTA) - Whole Blood
Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, bone marrow touch prep slides, cerebrospinal fluid (CSF)

Transport Temperature

Room Temperature

Specimen Stability

Sample quality will be determined by testing facility. It is best for specimens to ship the same day as collected.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Broken or dirty slides, excessive cellular debris or stained slides, frozen specimen

Methodology
Fluorescence in situ Hybridization (FISH)

Report Available

3-5 days

Clinical Significance

Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones .

Performing Laboratory
LabCorp

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.